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Autistic spectrum disorder (ASD) is a common, persistent, and neurobiological disorder characterized by impaired social and communication skills and repetitive and restricted patterns of behaviors and interests. The present study aimed to investigate the association between catechol-O-methyltransferase (COMT) gene polymorphism and autistic-like behaviors in ASD patients. A total of 110 ASD patients and 110 healthy controls were enrolled in this study. All patients were diagnosed according to DSM-IV criteria for ASD. The autistic-like behaviors of ASD patients were assessed by the parent-rated Aberrant Behavior Checklist (ABC), Child Behavior Checklist (CBCL), and Social Responsiveness Scale (SRS). The c.472G>A polymorphism in the COMT gene was genotyped using the real-time polymerase chain reaction (PCR). The results revealed that the mutation -A allele was significantly associated with poor SRS score (P = 0.004) and total score (P = 0.018) in ASD patients. In the same group of patients, there was also a significant association between the -A allele and total score of ABC (P = 0.002). In addition, total score of ABC was significantly higher in -A carriers compared with GG group (P = 0.003). The present findings suggest that -A allele polymorphism in COMT gene might increase the risk of ASD. The -A allele might be a functional variant of the COMT gene, which is associated with increased risk of ASD.Q: Difficulty getting subfolders of a folder using Ant? I have an Ant build file that essentially is a template build file. This build file is supposed to find all.xml files in the current folder (and any subfolders) and process them. 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